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PARP1 gene expression is downregulated by knockdown of PARG gene

Poly(ADP-ribosyl)ation is a modification of nuclear proteins that regulates DNA replication, repair and transcription. In order to investigate the biological effects of degradation of poly(ADP-ribose), knockdown of the poly(ADP-ribose) glycohydrolase (PARG) gene was performed by introducing a short...

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Detalles Bibliográficos
Autores principales: UCHIUMI, FUMIAKI, WATANABE, TAKESHI, OHTA, RYO, ABE, HIDEAKI, TANUMA, SEI-ICHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658849/
https://www.ncbi.nlm.nih.gov/pubmed/23467693
http://dx.doi.org/10.3892/or.2013.2321