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Apelin elevates blood pressure in ICR mice with L-NAME-induced endothelial dysfunction

Apelin is the endogenous ligand of APJ, which belongs to the family of G protein-coupled receptors. Apelin and APJ are highly expressed in various cardiovascular tissues, including the heart, kidney and vascular endothelial and smooth muscle cells. Although apelin exerts hypotensive effects via acti...

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Detalles Bibliográficos
Autores principales: NAGANO, KATSUMASA, ISHIDA, JUNJI, UNNO, MADOKA, MATSUKURA, TANOMU, FUKAMIZU, AKIYOSHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658861/
https://www.ncbi.nlm.nih.gov/pubmed/23525196
http://dx.doi.org/10.3892/mmr.2013.1378