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Apelin elevates blood pressure in ICR mice with L-NAME-induced endothelial dysfunction
Apelin is the endogenous ligand of APJ, which belongs to the family of G protein-coupled receptors. Apelin and APJ are highly expressed in various cardiovascular tissues, including the heart, kidney and vascular endothelial and smooth muscle cells. Although apelin exerts hypotensive effects via acti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658861/ https://www.ncbi.nlm.nih.gov/pubmed/23525196 http://dx.doi.org/10.3892/mmr.2013.1378 |