RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation

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In the present study, we downregulated FANCF expression by small interfering RNA (siRNA) in OVCAR ovarian cancer cells to address the effects of decreased FANCF expression on the function of the Fanconi anemia (FA)/breast cancer susceptibility gene (BRCA) pathway. Furthermore, we investigated whethe...

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Detalles Bibliográficos
Autores principales: HE, MIAO, SUN, HAI-GANG, HAO, JUN-YING, LI, YAN-LIN, YU, JIAN-KUN, YAN, YUAN-YUAN, ZHAO, LIN, LI, NA, WANG, YAN, BAI, XUE-FENG, YU, ZHAO-JIN, ZHENG, ZHI-HONG, MI, XIAO-YI, WANG, EN-HUA, WEI, MIN-JIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658863/
https://www.ncbi.nlm.nih.gov/pubmed/23440494
http://dx.doi.org/10.3892/or.2013.2295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658863/
https://www.ncbi.nlm.nih.gov/pubmed/23440494
http://dx.doi.org/10.3892/or.2013.2295

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