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Gene expression profiling of chronic myeloid leukemia with variant t(9;22) reveals a different signature from cases with classic translocation

BACKGROUND: The t(9;22)(q34;q11) generating the BCR/ABL1 fusion gene represents the cytogenetic hallmark of chronic myeloid leukemia (CML). About 5–10% of CML cases show variant translocations with the involvement of other chromosomes in addition to chromosomes 9 and 22. The molecular bases of biolo...

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Detalles Bibliográficos
Autores principales: Albano, Francesco, Zagaria, Antonella, Anelli, Luisa, Coccaro, Nicoletta, Impera, Luciana, Minervini, Crescenzio Francesco, Minervini, Angela, Rossi, Antonella Russo, Tota, Giuseppina, Casieri, Paola, Specchia, Giorgina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658885/
https://www.ncbi.nlm.nih.gov/pubmed/23642027
http://dx.doi.org/10.1186/1476-4598-12-36