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AKT activation by N-cadherin regulates beta-catenin signaling and neuronal differentiation during cortical development

BACKGROUND: During cerebral cortical development, neural precursor-precursor interactions in the ventricular zone neurogenic niche coordinate signaling pathways that regulate proliferation and differentiation. Previous studies with shRNA knockdown approaches indicated that N-cadherin adhesion betwee...

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Detalles Bibliográficos
Autores principales: Zhang, Jianing, Shemezis, Julie R, McQuinn, Erin R, Wang, Jing, Sverdlov, Maria, Chenn, Anjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658902/
https://www.ncbi.nlm.nih.gov/pubmed/23618343
http://dx.doi.org/10.1186/1749-8104-8-7