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Temporal changes of cytochrome P450 (Cyp) and eicosanoid-related gene expression in the rat brain after traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) induces arachidonic acid (ArA) release from cell membranes. ArA metabolites form a class of over 50 bioactive eicosanoids that can induce both adaptive and/or maladaptive brain responses. The dynamic metabolism of ArA to eicosanoids, and how they affect the i...

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Detalles Bibliográficos
Autores principales: Birnie, Matthew, Morrison, Ryan, Camara, Ramatoulie, Strauss, Kenneth I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658912/
https://www.ncbi.nlm.nih.gov/pubmed/23642095
http://dx.doi.org/10.1186/1471-2164-14-303