Empirical Bayes estimation of posterior probabilities of enrichment: A comparative study of five estimators of the local false discovery rate

BACKGROUND: In investigating differentially expressed genes or other selected features, researchers conduct hypothesis tests to determine which biological categories, such as those of the Gene Ontology (GO), are enriched for the selected features. Multiple comparison procedures (MCPs) are commonly u...

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Detalles Bibliográficos
Autores principales: Yang, Zhenyu, Li, Zuojing, Bickel, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658916/
https://www.ncbi.nlm.nih.gov/pubmed/23497228
http://dx.doi.org/10.1186/1471-2105-14-87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658916/
https://www.ncbi.nlm.nih.gov/pubmed/23497228
http://dx.doi.org/10.1186/1471-2105-14-87

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