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Normal cognition in transgenic BRI2-Aβ mice

BACKGROUND: Recent research in Alzheimer’s disease (AD) field has been focused on the potential role of the amyloid-β protein that is derived from the transmembrane amyloid precursor protein (APP) in directly mediating cognitive impairment in AD. Transgenic mouse models overexpressing APP develop ro...

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Detalles Bibliográficos
Autores principales: Kim, Jungsu, Chakrabarty, Paramita, Hanna, Amanda, March, Amelia, Dickson, Dennis W, Borchelt, David R, Golde, Todd, Janus, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658944/
https://www.ncbi.nlm.nih.gov/pubmed/23663320
http://dx.doi.org/10.1186/1750-1326-8-15