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Normal cognition in transgenic BRI2-Aβ mice
BACKGROUND: Recent research in Alzheimer’s disease (AD) field has been focused on the potential role of the amyloid-β protein that is derived from the transmembrane amyloid precursor protein (APP) in directly mediating cognitive impairment in AD. Transgenic mouse models overexpressing APP develop ro...
Autores principales: | Kim, Jungsu, Chakrabarty, Paramita, Hanna, Amanda, March, Amelia, Dickson, Dennis W, Borchelt, David R, Golde, Todd, Janus, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658944/ https://www.ncbi.nlm.nih.gov/pubmed/23663320 http://dx.doi.org/10.1186/1750-1326-8-15 |
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