ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice

BACKGROUND: Recent findings suggest that the pathological effects of apoE4, the most prevalent genetic risk factor for Alzheimer’s disease (AD), start many years before the onset of the disease and are already detectable at a young age. In the present study we investigated the extent to which such p...

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Detalles Bibliográficos
Autores principales: Liraz, Ori, Boehm-Cagan, Anat, Michaelson, Daniel M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659080/
https://www.ncbi.nlm.nih.gov/pubmed/23684315
http://dx.doi.org/10.1186/1750-1326-8-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659080/
https://www.ncbi.nlm.nih.gov/pubmed/23684315
http://dx.doi.org/10.1186/1750-1326-8-16

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