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Liver-derived endocrine IGF-I is not critical for activation of skeletal muscle protein synthesis following oral feeding

BACKGROUND: Insulin-like growth factor-1 (IGF-1) is produced in various tissues to stimulate protein synthesis under different conditions. It is however, difficult to distinguish effects by locally produced IGF-1 compared to liver-derived IGF-1 appearing in the circulation. In the present study the...

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Detalles Bibliográficos
Autores principales: Iresjö, Britt-Marie, Svensson, Johan, Ohlsson, Claes, Lundholm, Kent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659091/
https://www.ncbi.nlm.nih.gov/pubmed/23657003
http://dx.doi.org/10.1186/1472-6793-13-7