Ageing Fxr Deficient Mice Develop Increased Energy Expenditure, Improved Glucose Control and Liver Damage Resembling NASH

Nuclear receptor subfamily 1, group H, member 4 (Nr1h4, FXR) is a bile acid activated nuclear receptor mainly expressed in the liver, intestine, kidney and adrenal glands. Upon activation, the primary function is to suppress cholesterol 7 alpha-hydroxylase (Cyp7a1), the rate-limiting enzyme in the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Bjursell, Mikael, Wedin, Marianne, Admyre, Therése, Hermansson, Majlis, Böttcher, Gerhard, Göransson, Melker, Lindén, Daniel, Bamberg, Krister, Oscarsson, Jan, Bohlooly-Y, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659114/
https://www.ncbi.nlm.nih.gov/pubmed/23700488
http://dx.doi.org/10.1371/journal.pone.0064721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659114/
https://www.ncbi.nlm.nih.gov/pubmed/23700488
http://dx.doi.org/10.1371/journal.pone.0064721

Ejemplares similares