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Crystal Structures of Carbamate Kinase from Giardia lamblia Bound with Citric Acid and AMP-PNP

The parasite Giardia lamblia utilizes the L-arginine dihydrolase pathway to generate ATP from L-arginine. Carbamate kinase (CK) catalyzes the last step in this pathway, converting ADP and carbamoyl phosphate to ATP and ammonium carbamate. Because the L-arginine pathway is essential for G. lamblia su...

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Detalles Bibliográficos
Autores principales: Lim, Kap, Kulakova, Liudmila, Galkin, Andrey, Herzberg, Osnat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659122/
https://www.ncbi.nlm.nih.gov/pubmed/23700444
http://dx.doi.org/10.1371/journal.pone.0064004