Preclinical study and phase I clinical safety evaluation of recombinant Mycobacterium tuberculosis ESAT6 protein

BACKGROUND: To investigate the ability of rESAT6 to identify different mycobacteria-sensitized guinea pigs and its safety in preclinical and phase I clinical study. MATERIAL/METHODS: Guinea pigs were sensitized with different Mycobacteria. After sensitization, all animals were intradermally injected...

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Detalles Bibliográficos
Autores principales: Du, Wei-Xin, Chen, Bao-Wen, Lu, Jin-Biao, Gao, Meng-Qiu, Shen, Xiao-Bing, Yang, Lei, Su, Cheng, Wang, Guo-Zhi, Sun, Qing-feng, Xu, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2013
Materias:
Animal Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659126/
https://www.ncbi.nlm.nih.gov/pubmed/23676766
http://dx.doi.org/10.12659/MSMBR.883912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659126/
https://www.ncbi.nlm.nih.gov/pubmed/23676766
http://dx.doi.org/10.12659/MSMBR.883912

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