Intracellular Interleukin-1 Receptor 2 Binding Prevents Cleavage and Activity of Interleukin-1α, Controlling Necrosis-Induced Sterile Inflammation

Necrosis can induce profound inflammation or be clinically silent. However, the mechanisms underlying such tissue specificity are unknown. Interleukin-1α (IL-1α) is a key danger signal released upon necrosis that exerts effects on both innate and adaptive immunity and is considered to be constitutiv...

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Detalles Bibliográficos
Autores principales: Zheng, Yue, Humphry, Melanie, Maguire, Janet J., Bennett, Martin R., Clarke, Murray C.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659285/
https://www.ncbi.nlm.nih.gov/pubmed/23395675
http://dx.doi.org/10.1016/j.immuni.2013.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659285/
https://www.ncbi.nlm.nih.gov/pubmed/23395675
http://dx.doi.org/10.1016/j.immuni.2013.01.008

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