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Direct Transmembrane Interaction between Actin and the Pore-Competent, Cholesterol-Dependent Cytolysin Pneumolysin

The eukaryotic actin cytoskeleton is an evolutionarily well-established pathogen target, as a large number of bacterial factors disturb its dynamics to alter the function of the host cells. These pathogenic factors modulate or mimic actin effector proteins or they modify actin directly, leading to a...

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Detalles Bibliográficos
Autores principales: Hupp, Sabrina, Förtsch, Christina, Wippel, Carolin, Ma, Jiangtao, Mitchell, Timothy J., Iliev, Asparouh I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659287/
https://www.ncbi.nlm.nih.gov/pubmed/23219469
http://dx.doi.org/10.1016/j.jmb.2012.11.034