Hec1-Dependent Cyclin B2 Stabilization Regulates the G2-M Transition and Early Prometaphase in Mouse Oocytes

The functions of the Ndc80/Hec1 subunit of the highly conserved Ndc80 kinetochore complex are normally restricted to M phase when it exerts a pivotal kinetochore-based role. Here, we find that in mouse oocytes, depletion of Hec1 severely compromises the G2-M transition because of impaired activation...

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Detalles Bibliográficos
Autores principales: Gui, Liming, Homer, Hayden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659288/
https://www.ncbi.nlm.nih.gov/pubmed/23541922
http://dx.doi.org/10.1016/j.devcel.2013.02.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659288/
https://www.ncbi.nlm.nih.gov/pubmed/23541922
http://dx.doi.org/10.1016/j.devcel.2013.02.008

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