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Involvement of Nrf2-Mediated Upregulation of Heme Oxygenase-1 in Mollugin-Induced Growth Inhibition and Apoptosis in Human Oral Cancer Cells

Although previous studies have shown that mollugin, a bioactive phytochemical isolated from Rubia cordifolia L. (Rubiaceae), exhibits antitumor effects, its biological activity in oral cancer has not been reported. We thus investigated the effects and putative mechanism of apoptosis induced by mollu...

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Detalles Bibliográficos
Autores principales: Lee, Young-Man, Auh, Q-Schick, Lee, Deok-Won, Kim, Jun-Yeol, Jung, Ha-Jin, Lee, Seung-Ho, Kim, Eun-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659465/
https://www.ncbi.nlm.nih.gov/pubmed/23738323
http://dx.doi.org/10.1155/2013/210604