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Ginsenoside Rp(1), a Ginsenoside Derivative, Blocks Promoter Activation of iNOS and COX-2 Genes by Suppression of an IKKβ-mediated NF-кB Pathway in HEK293 Cells

Ginsenoside (G) Rp(1) is a ginseng saponin derivative with anti-cancer and anti-inflammatory activities. In this study, we examined the mechanism by which G-Rp(1) inhibits inflammatory responses of cells. We did this using a strategy in which DNA constructs containing cyclooxygenase (COX)-2 and indu...

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Detalles Bibliográficos
Autores principales: Shen, Ting, Lee, Jaehwi, Park, Myung Hwan, Lee, Yong Gyu, Rho, Ho Sik, Kwak, Yi-Seong, Rhee, Man Hee, Park, Yung Chul, Cho, Jae Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Ginseng 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659523/
https://www.ncbi.nlm.nih.gov/pubmed/23717062
http://dx.doi.org/10.5142/jgr.2011.35.2.200