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Anti-apoptotic Activity of Ginsenoside Rb(1) in Hydrogen Peroxide-treated Chondrocytes: Stabilization of Mitochondria and the Inhibition of Caspase-3

Chondrocyte apoptosis has been recognized as an important factor in the pathogenesis of osteoarthritis (OA). Hydrogen peroxide (H(2)O(2)), which produces reactive oxygen species, reportedly induces apoptosis in chondrocytes. The ginsenoside Rb(1) (GRb(1)) is the principal component in ginseng and ha...

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Detalles Bibliográficos
Autores principales: Na, Ji-Young, Kim, Sokho, Song, Kibbeum, Lim, Kyu-Hee, Shin, Gee-Wook, Kim, Jong-Hoon, Kim, Bumseok, Kwon, Young-Bae, Kwon, Jungkee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Ginseng 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659597/
https://www.ncbi.nlm.nih.gov/pubmed/23717124
http://dx.doi.org/10.5142/jgr.2012.36.3.242