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Compartmentalization of metabolic pathways in yeast mitochondria improves production of branched chain alcohols
Efforts to improve the production of a compound of interest in Saccharomyces cerevisiae have mainly involved engineering or overexpression of cytoplasmic enzymes. We show that targeted expression of metabolic pathways to mitochondria can increase production levels compared with expression of the sam...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659820/ https://www.ncbi.nlm.nih.gov/pubmed/23417095 http://dx.doi.org/10.1038/nbt.2509 |