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MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts

BACKGROUND: Although various microRNAs (miRNAs) regulate immune and inflammatory responses, the function of miRNAs in periodontitis has not been clearly illuminated. In this study, we measured miRNA-146 (miRNA-146a and miRNA-146b-5p) expression and explored its regulatory function in the inflammator...

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Detalles Bibliográficos
Autores principales: Xie, Yu-Feng, Shu, Rong, Jiang, Shao-Yun, Liu, Da-Li, Ni, Jing, Zhang, Xiu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660163/
https://www.ncbi.nlm.nih.gov/pubmed/23680172
http://dx.doi.org/10.1186/1476-9255-10-20