Cargando…

MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts

BACKGROUND: Although various microRNAs (miRNAs) regulate immune and inflammatory responses, the function of miRNAs in periodontitis has not been clearly illuminated. In this study, we measured miRNA-146 (miRNA-146a and miRNA-146b-5p) expression and explored its regulatory function in the inflammator...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Yu-Feng, Shu, Rong, Jiang, Shao-Yun, Liu, Da-Li, Ni, Jing, Zhang, Xiu-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660163/ https://www.ncbi.nlm.nih.gov/pubmed/23680172 http://dx.doi.org/10.1186/1476-9255-10-20

Ejemplares similares

miRNA-146 negatively regulates the production of pro-inflammatory cytokines via NF-κB signalling in human gingival fibroblasts
por: Xie, Yu-feng, et al.
Publicado: (2014)

The Newly Discovered Cytokine IL-34 Is Expressed in Gingival Fibroblasts, Shows Enhanced Expression by Pro-Inflammatory Cytokines, and Stimulates Osteoclast Differentiation
por: Boström, Elisabeth A., et al.
Publicado: (2013)

Human gingival fibroblasts: Isolation, characterization, and evaluation of CD146 expression
por: Diar-Bakirly, Samira, et al.
Publicado: (2021)

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts
por: Williams, Rachel C., et al.
Publicado: (2016)

Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines
por: Boström, Elisabeth A., et al.
Publicado: (2015)

Fungal metabolite (+)-terrein suppresses IL-6/sIL-6R-induced CSF1 secretion by inhibiting JAK1 phosphorylation in human gingival fibroblasts
por: Yamamoto, Satoshi, et al.
Publicado: (2018)

MicroRNA-146a inhibits NF-κB activation and pro-inflammatory cytokine production by regulating IRAK1 expression in THP-1 cells
por: Zhou, Chunlei, et al.
Publicado: (2019)

CDCP1 Identifies a CD146 Negative Subset of Marrow Fibroblasts Involved with Cytokine Production
por: Iwata, Mineo, et al.
Publicado: (2014)

Protein kinase A enhances lipopolysaccharide-induced IL-6, IL-8, and PGE(2 )production by human gingival fibroblasts
por: Ara, Toshiaki, et al.
Publicado: (2012)

Comparison of microRNA profiles of human periodontal diseased and healthy gingival tissues
por: Xie, Yu-feng, et al.
Publicado: (2011)

Palatal mucosa derived fibroblasts present an adaptive behavior regarding cytokine secretion when grafted onto the gingival margin
por: Azevedo, Fabíola Pontes, et al.
Publicado: (2014)

Areca nut exposure increases secretion of tumor‐promoting cytokines in gingival fibroblasts that trigger DNA damage in oral keratinocytes
por: Illeperuma, Rasika P., et al.
Publicado: (2015)

Autophagy upregulates inflammatory cytokines in gingival tissue of patients with periodontitis and lipopolysaccharide‐stimulated human gingival fibroblasts
por: Kim, Won Jae, et al.
Publicado: (2021)

MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways
por: Cheng, Henry S, et al.
Publicado: (2013)

Expression levels of novel cytokine IL-32 in periodontitis and its role in the suppression of IL-8 production by human gingival fibroblasts stimulated with Porphyromonas gingivalis
por: Ouhara, Kazuhisa, et al.
Publicado: (2012)

Inhibitors of DNA methylation support TGF-β1-induced IL11 expression in gingival fibroblasts
por: Sufaru, Irina-Georgeta, et al.
Publicado: (2017)

Camostat mesilate inhibits pro-inflammatory cytokine secretion and improves cell viability by regulating MFGE8 and HMGN1 in lipopolysaccharide-stimulated DF-1 chicken embryo fibroblasts
por: Yuan, Lin, et al.
Publicado: (2021)

Study on the Mechanism of miR-146a in Gingival Mesenchymal Stem Cells
por: Wang, Fang, et al.
Publicado: (2022)

Effect of Azithromycin on Proinflammatory Cytokine Production in Gingival Fibroblasts and the Remodeling of Periodontal Tissue
por: Nagano, Takatoshi, et al.
Publicado: (2020)

IL-17-differentiated macrophages secrete pro-inflammatory cytokines in response to oxidized low-density lipoprotein
por: de la Paz Sánchez-Martínez, María, et al.
Publicado: (2017)

Plasma microRNA-21, microRNA-146a and IL-13 expression in asthmatic children
por: Hammad Mahmoud Hammad, Reham, et al.
Publicado: (2018)

Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro-inflammatory cytokines in fibroblast-like synoviocytes in rheumatoid arthritis
por: Fan, Lieying, et al.
Publicado: (2012)

Secretion of pro‐inflammatory cytokines and chemokines and loss of regulatory signals by fibroblast‐like synoviocytes in juvenile idiopathic arthritis
por: Brescia, AnneMarie C., et al.
Publicado: (2017)

CEMP1 Induces Transformation in Human Gingival Fibroblasts
por: Bermúdez, Mercedes, et al.
Publicado: (2015)

Gingival Fibroblasts Are Sensitive to Oral Cell Lysates Indicated by Their IL11 Expression
por: Panahipour, Layla, et al.
Publicado: (2023)

Crosstalk between miR-146a and pro-inflammatory cytokines in patients with systemic lupus erythematosus
por: El-Akhras, Basima A, et al.
Publicado: (2023)

MicroRNA-146a downregulates the production of hyaluronic acid and collagen I in Graves' ophthalmopathy orbital fibroblasts
por: Liu, Wei, et al.
Publicado: (2020)

Ecklonia cava Extract Exerts Anti-Inflammatory Effect in Human Gingival Fibroblasts and Chronic Periodontitis Animal Model by Suppression of Pro-Inflammatory Cytokines and Chemokines
por: Jung, Jae-In, et al.
Publicado: (2021)

Salt-inducible kinases are required for the IL-33–dependent secretion of cytokines and chemokines in mast cells
por: Darling, Nicola J., et al.
Publicado: (2021)

Analysis of senescence in gingival tissues and gingival fibroblast cultures
por: Furukawa, Masae, et al.
Publicado: (2022)

Mast Cell Cytokines in Acute and Chronic Gingival Tissue Inflammation: Role of IL-33 and IL-37
por: Trimarchi, Matteo, et al.
Publicado: (2022)

Equine Placentitis in Mares Induces the Secretion of Pro-Inflammatory Cytokine eIL-1β and the Active Extracellular Matrix Metalloproteinase (MMP)-9
por: Morales-Vázquez, María Margarita, et al.
Publicado: (2023)

Role of immune-related lncRNAs--PRKCQ-AS1 and EGOT in the regulation of IL-1β, IL-6 and IL-8 expression in human gingival fibroblasts with TNF-α stimulation
por: Zhao, Quanquan, et al.
Publicado: (2023)

MicroRNA-146a-5p Negatively Regulates Pro-Inflammatory Cytokine Secretion and Cell Activation in Lipopolysaccharide Stimulated Human Hepatic Stellate Cells through Inhibition of Toll-Like Receptor 4 Signaling Pathways
por: Chen, Yuhan, et al.
Publicado: (2016)

Effect of novobiocin on the viability of human gingival fibroblasts (HGF-1)
por: Szkaradkiewicz, Anna K, et al.
Publicado: (2014)

TAS2R16 Activation Suppresses LPS-Induced Cytokine Expression in Human Gingival Fibroblasts
por: Zhou, Zhiyan, et al.
Publicado: (2021)

Data on pro-inflammatory cytokines IL-1β, IL-17, and IL-6 in the peripheral blood of HIV-infected individuals
por: Saing, Tommy, et al.
Publicado: (2016)

Influence of Diabetes Mellitus and Smoking on Pro- and Anti-Inflammatory Cytokine Profiles in Gingival Crevicular Fluid
por: Pasarin, Liliana, et al.
Publicado: (2023)

Role of Cyclosporine in Gingival Hyperplasia: An In Vitro Study on Gingival Fibroblasts
por: Lauritano, Dorina, et al.
Publicado: (2020)

An activated‐zinc oral rinse reduces pro‐inflammatory cytokine secretion and promotes proliferation in Porphyromonas gingivalis LPS‐challenged gingival tissues – A pilot study
por: Stanton, Kaitlyn A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4phiepq76geiochthjfmo42rb4