Human monoclonal ScFv that bind to different functional domains of M2 and inhibit H5N1 influenza virus replication

BACKGROUND: Novel effective anti-influenza agent that tolerates influenza virus antigenic variation is needed. Highly conserved influenza virus M2 protein has multiple pivotal functions including ion channel activity for vRNP uncoating, anti-autophagy and virus assembly, morphogenesis and release. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Pissawong, Tippawan, Maneewatch, Santi, Thueng-in, Kanyarat, Srimanote, Potjanee, Dong-din-on, Fonthip, Thanongsaksrikul, Jeeraphong, Songserm, Thaweesak, Tongtawe, Pongsri, Bangphoomi, Kunan, Chaicumpa, Wanpen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660209/
https://www.ncbi.nlm.nih.gov/pubmed/23672256
http://dx.doi.org/10.1186/1743-422X-10-148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660209/
https://www.ncbi.nlm.nih.gov/pubmed/23672256
http://dx.doi.org/10.1186/1743-422X-10-148

Ejemplares similares