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PEP-1-CAT protects hypoxia/reoxygenation-induced cardiomyocyte apoptosis through multiple sigaling pathways

BACKGROUND: Catalase (CAT) breaks down H(2)O(2) into H(2)O and O(2) to protects cells from oxidative damage. However, its translational potential is limited because exogenous CAT cannot enter living cells automatically. This study is aimed to investigate if PEP-1-CAT fusion protein can effectively p...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Wei, Shuang, Tang, Jun-Ming, Guo, Ling-Yun, Zheng, Fei, Yang, Jian-Ye, Kong, Xia, Huang, Yong-Zhang, Chen, Shi-You, Wang, Jia-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660214/
https://www.ncbi.nlm.nih.gov/pubmed/23642335
http://dx.doi.org/10.1186/1479-5876-11-113