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Stromal cell derived factor-1alpha protects stem cell derived insulin-producing cells from glucotoxicity under high glucose conditions in-vitro and ameliorates drug induced diabetes in rats

BACKGROUND: Diabetes mellitus is affecting more than 300 million people worldwide. Current treatment strategies cannot prevent secondary complications. Stem cells due to their regenerative power have long been the attractive target for the cell-based therapies. Mesenchymal stem cells (MSCs) possess...

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Detalles Bibliográficos
Autores principales: Tariq, Muhammad, Masoud, Muhammad Sharif, Mehmood, Azra, Khan, Shaheen N, Riazuddin, Sheikh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660237/
https://www.ncbi.nlm.nih.gov/pubmed/23648189
http://dx.doi.org/10.1186/1479-5876-11-115