Elimination of Self-Reactive T Cells in the Thymus: A Timeline for Negative Selection

The elimination of autoreactive T cells occurs via thymocyte apoptosis and removal by thymic phagocytes, but the sequence of events in vivo, and the relationship between thymocyte death and phagocytic clearance, are unknown. Here we address these questions by following a synchronized cohort of thymo...

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Detalles Bibliográficos
Autores principales: Dzhagalov, Ivan Lilyanov, Chen, Katherine Grace, Herzmark, Paul, Robey, Ellen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660248/
https://www.ncbi.nlm.nih.gov/pubmed/23700386
http://dx.doi.org/10.1371/journal.pbio.1001566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660248/
https://www.ncbi.nlm.nih.gov/pubmed/23700386
http://dx.doi.org/10.1371/journal.pbio.1001566

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