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Diurnal variation of phenylalanine and tyrosine concentrations in adult patients with phenylketonuria: subcutaneous microdialysis is no adequate tool for the determination of amino acid concentrations

BACKGROUND: Metabolic control and dietary management of patients with phenylketonuria (PKU) are based on single blood samples obtained at variable intervals. Sampling conditions are often not well-specified and intermittent variation of phenylalanine concentrations between two measurements remains u...

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Detalles Bibliográficos
Autores principales: Grünert, Sarah C, Brichta, Corinna M, Krebs, Andreas, Clement, Hans-Willi, Rauh, Reinhold, Fleischhaker, Christian, Hennighausen, Klaus, Sass, Jörn Oliver, Schwab, K Otfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660276/
https://www.ncbi.nlm.nih.gov/pubmed/23672685
http://dx.doi.org/10.1186/1475-2891-12-60