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Time course changes of anti- and pro-apoptotic proteins in apigenin-induced genotoxicity

BACKGROUND: Apigenin (4′,5,7-trihydroxyflavone, AP), an active component of many medicinal Chinese herbs, exhibits anticancer properties in vitro and in vivo. This study aims to investigate the genotoxic, cytostatic, and cytotoxic effects of AP and time course changes in the levels of anti- and pro-...

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Detalles Bibliográficos
Autores principales: Papachristou, Fotini, Chatzaki, Ekaterini, Petrou, Athanasios, Kougioumtzi, Ioanna, Katsikogiannis, Nikolaos, Papalambros, Alexandros, Tripsianis, Grigorios, Simopoulos, Constantinos, Tsaroucha, Alexandra K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660279/
https://www.ncbi.nlm.nih.gov/pubmed/23642018
http://dx.doi.org/10.1186/1749-8546-8-9