Cargando…

Functional Interrogation of an Odorant Receptor Locus Reveals Multiple Axes of Transcriptional Regulation

The odorant receptor (OR) genes constitute the largest mammalian gene family and are expressed in a monogenic and monoallelic fashion, through an unknown mechanism that likely exploits positive and negative regulation. We devised a genetic strategy in mice to examine OR selection by determining the...

Descripción completa

Detalles Bibliográficos
Autores principales: Fleischmann, Alexander, Abdus-Saboor, Ishmail, Sayed, Atef, Shykind, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660300/
https://www.ncbi.nlm.nih.gov/pubmed/23700388
http://dx.doi.org/10.1371/journal.pbio.1001568