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Substrate Specificity Provides Insights into the Sugar Donor Recognition Mechanism of O-GlcNAc Transferase (OGT)

O-Linked β-N-acetylglucosaminyl transferase (OGT) plays an important role in the glycosylation of proteins, which is involved in various cellular events. In human, three isoforms of OGT (short OGT [sOGT]; mitochondrial OGT [mOGT]; and nucleocytoplasmic OGT [ncOGT]) share the same catalytic domain, i...

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Detalles Bibliográficos
Autores principales: Ma, Xiaofeng, Liu, Pi, Yan, Hui, Sun, Hong, Liu, Xiaoyan, Zhou, Feng, Li, Lei, Chen, Yi, Muthana, Musleh M., Chen, Xi, Wang, Peng G., Zhang, Lianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660302/
https://www.ncbi.nlm.nih.gov/pubmed/23700425
http://dx.doi.org/10.1371/journal.pone.0063452