Mapping and Exome Sequencing Identifies a Mutation in the IARS Gene as the Cause of Hereditary Perinatal Weak Calf Syndrome

We identified an IARS (isoleucyl-tRNA synthetase) c.235G>C (p.Val79Leu) substitution as the causative mutation for neonatal weakness with intrauterine growth retardation (perinatal weak calf syndrome). In Japanese Black cattle, the syndrome was frequently found in calves sired by Bull A. Hence, w...

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Detalles Bibliográficos
Autores principales: Hirano, Takashi, Kobayashi, Naohiko, Matsuhashi, Tamako, Watanabe, Daisaku, Watanabe, Toshio, Takasuga, Akiko, Sugimoto, Mayumi, Sugimoto, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660308/
https://www.ncbi.nlm.nih.gov/pubmed/23700453
http://dx.doi.org/10.1371/journal.pone.0064036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660308/
https://www.ncbi.nlm.nih.gov/pubmed/23700453
http://dx.doi.org/10.1371/journal.pone.0064036

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