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A Novel Epitope from CD22 Regulates Th1 and Th17 Cell Function in Systemic Lupus Erythematosus

The published antibodies (Abs) against CD22 on B cells including Epratuzumab could inhibit B cell activation mainly through binding to C2-set Ig domain of CD22, but they are rarely reported to modulate the pathogenic CD4(+) T cell function in systemic lupus erythematosus (SLE). Recently, it was prov...

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Detalles Bibliográficos
Autores principales: Yuan, Jing, Yu, Miao, Cao, Ai-Lin, Chen, Xiao, Zhang, Li-Hua, Song, You, Cheng, Xiang, Zhou, Zi-Hua, Wang, Min, Guo, He-Ping, Du, Rong, Liao, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660346/
https://www.ncbi.nlm.nih.gov/pubmed/23704998
http://dx.doi.org/10.1371/journal.pone.0064572