Small Heterodimer Partner-Targeting Therapy Inhibits Systemic Inflammatory Responses through Mitochondrial Uncoupling Protein 2

The orphan nuclear receptor, small heterodimer partner (SHP), appears to play a negative regulatory role in innate immune signaling. Emerging evidence warrants further study on the therapeutic targeting of SHP to suppress excessive and deleterious inflammation. Here we show that fenofibrate, which t...

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Detalles Bibliográficos
Autores principales: Yang, Chul-Su, Yuk, Jae-Min, Kim, Jwa-Jin, Hwang, Jung Hwan, Lee, Chul-Ho, Kim, Jin-Man, Oh, Goo Taeg, Choi, Hueng-Sik, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660347/
https://www.ncbi.nlm.nih.gov/pubmed/23704907
http://dx.doi.org/10.1371/journal.pone.0063435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660347/
https://www.ncbi.nlm.nih.gov/pubmed/23704907
http://dx.doi.org/10.1371/journal.pone.0063435

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