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Sterigmatocystin-Induced DNA Damage Triggers G(2) Arrest via an ATM/p53-Related Pathway in Human Gastric Epithelium GES-1 Cells In Vitro

Sterigmatocystin (ST), which is commonly detected in food and feed commodities, is a mutagenic and carcinogenic mycotoxin that has been recognized as a possible human carcinogen. Our previous study showed that ST can induce G(2) phase arrest in GES-1 cells in vitro and that the MAPK and PI3K signali...

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Detalles Bibliográficos
Autores principales: Zhang, Donghui, Cui, Yu, Shen, Haitao, Xing, Lingxiao, Cui, Jinfeng, Wang, Juan, Zhang, Xianghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660384/
https://www.ncbi.nlm.nih.gov/pubmed/23705030
http://dx.doi.org/10.1371/journal.pone.0065044