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Sterigmatocystin-Induced DNA Damage Triggers G(2) Arrest via an ATM/p53-Related Pathway in Human Gastric Epithelium GES-1 Cells In Vitro
Sterigmatocystin (ST), which is commonly detected in food and feed commodities, is a mutagenic and carcinogenic mycotoxin that has been recognized as a possible human carcinogen. Our previous study showed that ST can induce G(2) phase arrest in GES-1 cells in vitro and that the MAPK and PI3K signali...
Autores principales: | Zhang, Donghui, Cui, Yu, Shen, Haitao, Xing, Lingxiao, Cui, Jinfeng, Wang, Juan, Zhang, Xianghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660384/ https://www.ncbi.nlm.nih.gov/pubmed/23705030 http://dx.doi.org/10.1371/journal.pone.0065044 |
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