Tumor Necrosis Factor-α and Lymphotoxin-α Mediate Myocardial Ischemic Injury via TNF Receptor 1, but Are Cardioprotective When Activating TNF Receptor 2

OBJECTIVE: This study determines the roles of tumor necrosis factor-α (TNFα) and lymphotoxin-α (LTα) in post-myocardial infarction (post-MI) cardiac injury, and identifies the TNF receptor type responsible for TNFα- and LTα-mediated cardiac injury. METHODS AND RESULTS: Adult male wild type (WT), TNF...

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Detalles Bibliográficos
Autores principales: Zhang, Yanqing, Zhao, Jianli, Lau, Wayne Bond, Jiao, Li-Yuan, Liu, Baojiang, Yuan, Yuexing, Wang, Xiaoliang, Gao, Erhe, Koch, Walter J., Ma, Xin-Liang, Wang, Yajing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660398/
https://www.ncbi.nlm.nih.gov/pubmed/23704873
http://dx.doi.org/10.1371/journal.pone.0060227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660398/
https://www.ncbi.nlm.nih.gov/pubmed/23704873
http://dx.doi.org/10.1371/journal.pone.0060227

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