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Androgen Receptor Promotes Ligand-Independent Prostate Cancer Progression through c-Myc Upregulation
The androgen receptor (AR) is the principal therapeutic target in prostate cancer. For the past 70 years, androgen deprivation therapy (ADT) has been the major therapeutic focus. However, some patients do not benefit, and those tumors that do initially respond to ADT eventually progress. One recentl...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660401/ https://www.ncbi.nlm.nih.gov/pubmed/23704919 http://dx.doi.org/10.1371/journal.pone.0063563 |