Areca Nut Extract Induces Pyknotic Necrosis in Serum-Starved Oral Cells via Increasing Reactive Oxygen Species and Inhibiting GSK3β: An Implication for Cytopathic Effects in Betel Quid Chewers

Areca nut has been proven to be correlated with various pathologic alterations in oral cavity. However, the mechanisms for such cytopathic effects are still elusive due mostly to the limitations of cell culture systems. Here we discovered that areca nut extract (ANE) induced production of autophagos...

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Detalles Bibliográficos
Autores principales: Ji, Wen-Tsai, Lee, Cheng-I, Chen, Jeff Yi-Fu, Cheng, Ya-Ping, Yang, Sheng-Ru, Chen, Jung-Hua, Chen, Hau-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660451/
https://www.ncbi.nlm.nih.gov/pubmed/23704899
http://dx.doi.org/10.1371/journal.pone.0063295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660451/
https://www.ncbi.nlm.nih.gov/pubmed/23704899
http://dx.doi.org/10.1371/journal.pone.0063295

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