Cargando…

Interaction between IGF-IR and ER Induced by E2 and IGF-I

Estrogen receptor (ER) is a nuclear receptor and the insulin-like growth factor-I (IGF-I) receptor (IGF-IR) is a transmembrane tyrosine kinase receptor. Estrogen and IGF-I are known to have synergistic effects on the growth of breast cancer cells. Recently, non-nuclear effects of ER have been under...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Zhenghong, Gao, Weimin, Jiang, Enze, Lu, Fang, Zhang, Luo, Shi, Zhaorong, Wang, Xinxing, Chen, Longbang, Lv, Tangfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660452/
https://www.ncbi.nlm.nih.gov/pubmed/23704881
http://dx.doi.org/10.1371/journal.pone.0062642