IL-17-committed Vγ4(+) γδ T cell deficiency in a spontaneous Sox13 mutant CD45.1 congenic mouse substrain protects from dermatitis

IL-17-committed γδ T (γδT17) cells participate in many immune responses but their developmental requirements and subset specific functions remain poorly understood. Here we report that a commonly used CD45.1(+) congenic C57BL/6 mouse substrain is characterized by a selective deficiency in Vγ4(+) γδT...

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Detalles Bibliográficos
Autores principales: Gray, Elizabeth E., Ramírez-Valle, Francisco, Xu, Ying, Wu, Shuang, Wu, Zhihao, Karjalainen, Klaus E., Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660499/
https://www.ncbi.nlm.nih.gov/pubmed/23624556
http://dx.doi.org/10.1038/ni.2585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660499/
https://www.ncbi.nlm.nih.gov/pubmed/23624556
http://dx.doi.org/10.1038/ni.2585

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