Regenerative Capacity of Old Muscle Stem Cells Declines without Significant Accumulation of DNA Damage

The performance of adult stem cells is crucial for tissue homeostasis but their regenerative capacity declines with age, leading to failure of multiple organs. In skeletal muscle this failure is manifested by the loss of functional tissue, the accumulation of fibrosis, and reduced satellite cell-med...

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Detalles Bibliográficos
Autores principales: Cousin, Wendy, Ho, Michelle Liane, Desai, Rajiv, Tham, Andrea, Chen, Robert Yuzen, Kung, Sunny, Elabd, Christian, Conboy, Irina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660529/
https://www.ncbi.nlm.nih.gov/pubmed/23704914
http://dx.doi.org/10.1371/journal.pone.0063528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660529/
https://www.ncbi.nlm.nih.gov/pubmed/23704914
http://dx.doi.org/10.1371/journal.pone.0063528

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