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Regenerative Capacity of Old Muscle Stem Cells Declines without Significant Accumulation of DNA Damage
The performance of adult stem cells is crucial for tissue homeostasis but their regenerative capacity declines with age, leading to failure of multiple organs. In skeletal muscle this failure is manifested by the loss of functional tissue, the accumulation of fibrosis, and reduced satellite cell-med...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660529/ https://www.ncbi.nlm.nih.gov/pubmed/23704914 http://dx.doi.org/10.1371/journal.pone.0063528 |