Deletion of the Prorenin Receptor from the Ureteric Bud Causes Renal Hypodysplasia

The role of the prorenin receptor (PRR) in the regulation of ureteric bud (UB) branching morphogenesis is unknown. Here, we investigated whether PRR acts specifically in the UB to regulate UB branching, kidney development and function. We demonstrate that embryonic (E) day E13.5 mouse metanephroi, i...

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Detalles Bibliográficos
Autores principales: Song, Renfang, Preston, Graeme, Ichihara, Atsuhiro, Yosypiv, Ihor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660567/
https://www.ncbi.nlm.nih.gov/pubmed/23704941
http://dx.doi.org/10.1371/journal.pone.0063835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660567/
https://www.ncbi.nlm.nih.gov/pubmed/23704941
http://dx.doi.org/10.1371/journal.pone.0063835

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