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Deletion of the Prorenin Receptor from the Ureteric Bud Causes Renal Hypodysplasia
The role of the prorenin receptor (PRR) in the regulation of ureteric bud (UB) branching morphogenesis is unknown. Here, we investigated whether PRR acts specifically in the UB to regulate UB branching, kidney development and function. We demonstrate that embryonic (E) day E13.5 mouse metanephroi, i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660567/ https://www.ncbi.nlm.nih.gov/pubmed/23704941 http://dx.doi.org/10.1371/journal.pone.0063835 |