The Intracellular Domain of Sortilin Interacts with Amyloid Precursor Protein and Regulates Its Lysosomal and Lipid Raft Trafficking

The processing of Amyloid precursor protein (APP) is multifaceted, comprising of protein transport, internalization and sequential proteolysis. However, the exact mechanism of APP intracellular trafficking and distribution remains unclear. To determine the interaction between sortilin and APP and th...

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Detalles Bibliográficos
Autores principales: Yang, Miao, Virassamy, Balaji, Vijayaraj, Swarna Lekha, Lim, Yoon, Saadipour, Khalil, Wang, Yan-Jiang, Han, Yan-Chuang, Zhong, Jin-Hua, Morales, Carlos R., Zhou, Xin-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660575/
https://www.ncbi.nlm.nih.gov/pubmed/23704887
http://dx.doi.org/10.1371/journal.pone.0063049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660575/
https://www.ncbi.nlm.nih.gov/pubmed/23704887
http://dx.doi.org/10.1371/journal.pone.0063049

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