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Dodecamer d-AGATCTAGATCT and a Homologous Hairpin form Triplex in the Presence of Peptide REWER

We have designed a dodecamer d-AGATCTAGATCT (RY12) with alternate oligopurines and oligopyrimidines tracts and its homologous 28 bp hairpin oligomer (RY28) that forms a triple helix only in the presence of a pentapeptide REWER. An intermolecular triplex is formed by the single strand invasion of the...

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Detalles Bibliográficos
Autores principales: Das, Amrita, Saha, Tapas, Ahmad, Faizan, Roy, Kunal B., Rishi, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660596/
https://www.ncbi.nlm.nih.gov/pubmed/23705027
http://dx.doi.org/10.1371/journal.pone.0065010