Differential Roles of PML Isoforms

The tumor suppressor promyelocytic leukemia (PML) protein is fused to the retinoic acid receptor alpha in patients suffering from acute promyelocytic leukemia (APL). Treatment of APL patients with arsenic trioxide (As(2)O(3)) reverses the disease phenotype by a process involving the degradation of t...

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Detalles Bibliográficos
Autores principales: Nisole, Sébastien, Maroui, Mohamed Ali, Mascle, Xavier H., Aubry, Muriel, Chelbi-Alix, Mounira K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660695/
https://www.ncbi.nlm.nih.gov/pubmed/23734343
http://dx.doi.org/10.3389/fonc.2013.00125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660695/
https://www.ncbi.nlm.nih.gov/pubmed/23734343
http://dx.doi.org/10.3389/fonc.2013.00125

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