MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

During inflammation and infection, hematopoietic stem and progenitor cells are stimulated to proliferate and differentiate into mature immune cells, especially of the myeloid lineage. MicroRNA-146a (miR-146a) is a critical negative regulator of inflammation. Deletion of miR-146a produces effects tha...

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Detalles Bibliográficos
Autores principales: Zhao, Jimmy L, Rao, Dinesh S, O’Connell, Ryan M, Garcia-Flores, Yvette, Baltimore, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660742/
https://www.ncbi.nlm.nih.gov/pubmed/23705069
http://dx.doi.org/10.7554/eLife.00537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660742/
https://www.ncbi.nlm.nih.gov/pubmed/23705069
http://dx.doi.org/10.7554/eLife.00537

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