Mesothelin Binding to CA125/MUC16 Promotes Pancreatic Cancer Cell Motility and Invasion via MMP-7 Activation

Mesothelin (MSLN) and cancer antigen125/mucin 16 (CA125/MUC16) are potential biomarkers for pancreatic cancer (PC) that are co-overexpressed at the invading edges of PC tissues, and their expression correlates with poor survival rates. However, the role of MSLN-MUC16 molecular interaction in PC cell...

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Detalles Bibliográficos
Autores principales: Chen, Shih-Hsun, Hung, Wei-Chien, Wang, Pu, Paul, Colin, Konstantopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660778/
https://www.ncbi.nlm.nih.gov/pubmed/23694968
http://dx.doi.org/10.1038/srep01870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660778/
https://www.ncbi.nlm.nih.gov/pubmed/23694968
http://dx.doi.org/10.1038/srep01870

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